Curcumin Extract for Prevention of Type 2 Diabetes
Turmeric Extract 100% Effective At Preventing Type 2 Diabetes, ADA Journal Study Finds
A remarkable human clinical study published in the journal Diabetes
Care, the journal of the American Diabetes Association, revealed that
turmeric extract was 100% successful at preventing prediabetic patients
from becoming diabetic over the course of a 9-month intervention.[1]
Performed by Thailand researchers, the study's primary object was to
assess the efficacy of curcumin, the primary polyphenol in turmeric
which gives the spice its golden hue, in delaying the development of
type 2 diabetes mellitus (T2DM) in a prediabetic population.
The study design was a randomized, double-blinded, placebo-controlled
trial including 240 subjects who met the American Diabetic Association's
criteria for prediabetes. All subjects were randomly assigned to
receive either 250 mg of curcuminoid or placebo capsules for 9 months.
Type 2 diabetes progression was assessed by measuring a wide range of
parameters, including changes in the insulin-producing cells within the
pancreas known as β-cells, insulin resistance, and the anti-inflammatory
cytokine known as adiponectin, at four different times: baseline, 3-,
6-, and 9-month visits during the course of intervention.
The results were reported as follows:
"After 9 months of treatment, 16.4% of subjects in the placebo group
were diagnosed with T2DM, whereas none were diagnosed with T2DM in the
curcumin-treated group. In addition, the curcumin-treated group showed a
better overall function of β-cells, with higher HOMA-β (61.58 vs.
48.72; P < 0.01) and lower C-peptide (1.7 vs. 2.17; P < 0.05). The
curcumin-treated group showed a lower level of HOMA-IR (3.22 vs. 4.04; P
< 0.001) and higher adiponectin (22.46 vs. 18.45; P < 0.05) when
compared with the placebo group." [emphasis added]
The researchers concluded:
"A 9-month curcumin intervention in a prediabetic population
significantly lowered the number of prediabetic individuals who
eventually developed T2DM. In addition, the curcumin treatment appeared
to improve overall function of β-cells, with very minor adverse effects.
Therefore, this study demonstrated that the curcumin intervention in a
prediabetic population may be beneficial."
A remarkable human clinical study published in the journal Diabetes Care, the journal of the American Diabetes Association, revealed that turmeric extract was 100% successful at preventing prediabetic patients from becoming diabetic over the course of a 9-month intervention.[1]
Performed by Thailand researchers, the study's primary object was to assess the efficacy of curcumin, the primary polyphenol in turmeric which gives the spice its golden hue, in delaying the development of type 2 diabetes mellitus (T2DM) in a prediabetic population.
The study design was a randomized, double-blinded, placebo-controlled trial including 240 subjects who met the American Diabetic Association's criteria for prediabetes. All subjects were randomly assigned to receive either 250 mg of curcuminoid or placebo capsules for 9 months.
Type 2 diabetes progression was assessed by measuring a wide range of parameters, including changes in the insulin-producing cells within the pancreas known as β-cells, insulin resistance, and the anti-inflammatory cytokine known as adiponectin, at four different times: baseline, 3-, 6-, and 9-month visits during the course of intervention.
The results were reported as follows:
"After 9 months of treatment, 16.4% of subjects in the placebo group were diagnosed with T2DM, whereas none were diagnosed with T2DM in the curcumin-treated group. In addition, the curcumin-treated group showed a better overall function of β-cells, with higher HOMA-β (61.58 vs. 48.72; P < 0.01) and lower C-peptide (1.7 vs. 2.17; P < 0.05). The curcumin-treated group showed a lower level of HOMA-IR (3.22 vs. 4.04; P < 0.001) and higher adiponectin (22.46 vs. 18.45; P < 0.05) when compared with the placebo group." [emphasis added]
The researchers concluded:
"A 9-month curcumin intervention in a prediabetic population significantly lowered the number of prediabetic individuals who eventually developed T2DM. In addition, the curcumin treatment appeared to improve overall function of β-cells, with very minor adverse effects. Therefore, this study demonstrated that the curcumin intervention in a prediabetic population may be beneficial."
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